Survey of Human Papillomavirus Types and Maternal-fetal Transmission in Pregnant Women
نویسندگان
چکیده
Background, In this study, we sought to determine the prevalence, types, and maternal-fetal transmission of HPV in pregnant women in Nanjing, Jiangsu Province. Results, The overall cervical HPV-DNA positivity rate among pregnant women was 13.44% (422/3139). The most frequently detected HPV types in mothers were HPV-16 (29.62%, 125/422), HPV-18 (14.69%, 62/422), and HPV-58 (14.22%, 60/422). The HPV-DNA concordance rate in maternal-neonatal pairs was 23.60% (55/233). HPV type-specific concordance occurred in 26 cases. Female neonates had a higher HPV-DNA positivity rate than males (17.69% vs. 11.65%). Conclusion: The cervical HPV-DNA positivity rate among pregnant women was 13.44% during pregnancy in Nanjing, China. The HPV-DNA transmission rate in maternal-neonatal pairs was 23.60%. The most frequently detected HPV genotype in pregnant women and newborns was HPV-16 in 46.38%. List of abbreviations: human papillomavirus (HPV) Corresponding author: Ying Hong
منابع مشابه
Survey of human papillomavirus types and their vertical transmission in pregnant women
BACKGROUND The prevalence, genotypes, and vertical transmission characteristics of human papillomavirus (HPV) among pregnant women from Nanjing, China was investigated. METHODS Cervical cells were collected from healthy pregnant women (n = 3139; stage of gestation, 24.6 ± 2.1 weeks) for cytological evaluation and determination of HPV infection status. Exfoliated oral and genital cells were co...
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